One green signal indicates one copy of the X chromosome and one orange signal indicates one copy of the Y chromosome.

Detects sex chromosome aneuploidies (Turner syndrome, Klinefelter syndrome) for rapid screening and diagnosis.

Used in prenatal diagnosis to identify sex chromosome abnormalities alongside autosomal trisomies. Applied for detecting tissue-specific sex chromosome mosaicism, especially high-level mosaicism. Identifies sex chromosome complement in paraffin-embedded tissues for clinical cytogenetics testing.