The CCND1 probe is located on chromosome 11 and the IGH probe is located on chromosome 14. A 450 Kb probe covering the CCND1 gene region at 11q13.3 is labeled with an orange dye, and A 1600 Kb probe covering the IGH gene region at 14q32.33 is labeled with a green dye.
Detects t(11;14) translocation in mantle cell lymphoma (MCL), multiple myeloma, chronic lymphocytic leukemia, and B-prolymphocytic leukemia. Used for differential diagnosis of CD5+ B-cell lymphoproliferative disorders, therapy response monitoring, and minimal residual disease detection. Essential for distinguishing atypical CLL from MCL patients.
| Product Description | Catalog No. | Specification | Certificate | Storage |
|---|---|---|---|---|
| CCND1/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401058-5 | 5 Tests | CE, ASR | Below 5°F (-15°C) |
| CCND1/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401058-10 | 10 Tests | CE, ASR | Below 5°F (-15°C) |
| CCND1/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401058-20 | 20 Tests | CE, ASR | Below 5°F (-15°C) |
