The CCND3 probe is located on chromosome 6 and the IGH probe is located on chromosome 14. An 800 Kb probe covering the CCND3 gene region at 6p21.1 is labeled with an orange dye, and A 1600 Kb probe covering the IGH gene region at 14q32.33 is labeled with a green dye.
Detects t(6;14) CCND3-IGH translocations in multiple myeloma patients as diagnostic aid and assists in disease monitoring. CCND3-IGH translocations are reported in plasma cell leukemia, diffuse large B-cell lymphoma (DLBCL) and splenic lymphomas with villous lymphocytes (SLVL). Used for identifying cyclin D3 dysregulation in B-cell malignancies and treatment stratification.
| Product Description | Catalog No. | Specification | Certificate | Storage |
|---|---|---|---|---|
| CCND3/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401064-5 | 5 Tests | CE, ASR | Below 5°F (-15°C) |
| CCND3/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401064-10 | 10 Tests | CE, ASR | Below 5°F (-15°C) |
| CCND3/IGH Dual Color, Dual Fusion FISH Probe Kit | JLB401064-20 | 20 Tests | CE, ASR | Below 5°F (-15°C) |
